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NSD1 抗体

This anti-NSD1 antibody is a 小鼠 单克隆 antibody detecting NSD1 in DB. Suitable for 人.
产品编号 ABIN932477
发货至: 中国

Quick Overview for NSD1 抗体 (ABIN932477)

抗原

See all NSD1 抗体
NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This NSD1 antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

2658C1a
  • 交叉反应

    交叉反应 (详细)

    Other species not studied.

    纯化方法

    Protein G affinity chromatography

    免疫原

    NSD1 antibody was raised in mouse using recombinant Human Nuclear Receptor Binding Set Domain Protein 1 (Nsd1)

    亚型

    IgG2b
  • 应用备注

    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    Lot specific

    缓冲液

    NSD1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • 抗原

    NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))

    别名

    NSD1

    背景

    This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98 kDa on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. Synonyms: Monoclonal NSD1 antibody, Anti-NSD1 antibody, Nuclear receptor binding SET domain protein 1 antibody, STO antibody, KMT3B antibody, SOTOS antibody, ARA267 antibody, FLJ22263 antibody, FLJ44628 antibody, DKFZp666C163 antibody.
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