Optimal conditions should be determined by the investigator.
限制
仅限研究用
浓度
Lot specific
缓冲液
SUPT4 H1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
储存液
Sodium azide
注意事项
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
注意事项
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
储存条件
4 °C/-20 °C
储存方法
Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
抗原
SUPT4H (SUPT4H1)
(Suppressor of Ty 4 Homolog 1 (SUPT4H1))
别名
SUPT4H1
背景
SUPT4H1 is a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. Synonyms: Monoclonal SUPT4H1 antibody, Anti-SUPT4H1 antibody, Suppressor of Ty 4 homolog 1 antibody, SPT4H antibody, SUPT4H antibody.