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MXI1 抗体

This anti-MXI1 antibody is a 小鼠 单克隆 antibody detecting MXI1 in DB. Suitable for 人.
产品编号 ABIN931182
发货至: 中国

Quick Overview for MXI1 抗体 (ABIN931182)

抗原

See all MXI1 抗体
MXI1 (MAX Interactor 1 (MXI1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MXI1 antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

MXI1C2a
  • 交叉反应

    交叉反应 (详细)

    Other species not studied.

    纯化方法

    Protein G affinity chromatography

    免疫原

    MXI1 antibody was raised in mouse using recombinant Human Max Interactor 1

    亚型

    IgG1
  • 应用备注

    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    Lot specific

    缓冲液

    MXI1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • 抗原

    MXI1 (MAX Interactor 1 (MXI1))

    别名

    MXI1

    背景

    Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Synonyms: Monoclonal MXI1 antibody, Anti-MXI1 antibody, MAX interacting protein 1 antibody, MAD2 antibody, MXD2 antibody, MXI antibody, MGC43220 antibody.

    途径

    Maintenance of Protein Location
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