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C14orf169 + NO66 抗体

The 小鼠 单克隆 anti-C14orf169 + NO66 antibody is suitable to detect C14orf169 + NO66 in samples from 人. It has been validated for DB.
产品编号 ABIN931094
发货至: 中国
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Quick Overview for C14orf169 + NO66 抗体 (ABIN931094)

抗原

See all C14orf169 + NO66 (C14orf169) 抗体
C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This C14orf169 + NO66 antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

3354C5a
  • 交叉反应

    交叉反应 (详细)

    Other species not studied.

    纯化方法

    Protein G affinity chromatography

    免疫原

    C14 orf169 antibody was raised in mouse using recombinant Human Chromosome 14 Open Reading Frame 169 (C14 rf169)

    亚型

    IgG1
  • 应用备注

    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    Lot specific

    缓冲液

    C14 orf169 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • 抗原

    C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))

    别名

    C14orf169

    背景

    C14orf169 encodes a histone demethylase that specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys 36' (H3K36me2). It also acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region. Synonyms: Monoclonal C14orf169 antibody, Anti-C14orf169 antibody, Chromosome 14 open reading frame 169 antibody, FLJ21802 antibody.
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