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Factor VIII 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects Factor VIII in WB. It exhibits reactivity toward 人.
产品编号 ABIN929428
发货至: 中国
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Quick Overview for Factor VIII 抗体 (C-Term) (ABIN929428)

抗原

See all Factor VIII (F8) 抗体
Factor VIII (F8) (Coagulation Factor VIII (F8))

适用

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宿主

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克隆类型

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多克隆

标记

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This Factor VIII antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    纯化方法

    Purified

    免疫原

    F8 antibody was raised in rabbit using the C terminal of F8 as the immunogen
  • 应用备注

    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    F8 Blocking Peptide, (ABIN938955), is also available for use as a blocking control in assays to test for specificity of this F8 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    Factor VIII (F8) (Coagulation Factor VIII (F8))

    别名

    F8

    背景

    This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. Synonyms: Polyclonal F8 antibody, Anti-F8 antibody, coagulation factor VIII, procoagulant component antibody, AHF antibody, DXS1253E antibody, F8B antibody, F8C antibody, FVIII antibody, HEMA antibody.
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