RASSF1 抗体 (C-Term)
Quick Overview for RASSF1 抗体 (C-Term) (ABIN929302)
抗原
See all RASSF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- RASSF1 antibody was raised in rabbit using the C terminal of RASSF1 as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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RASSF1 Blocking Peptide, (ABIN940157), is also available for use as a blocking control in assays to test for specificity of this RASSF1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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别名
- RASSF1
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背景
- This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Synonyms: Polyclonal RASSF1 antibody, Anti-RASSF1 antibody, Ras association, RalGDS/AF-6 domain family member 1 antibody, 123F2 antibody, NORE2A antibody, RASSF1A antibody, RDA32 antibody, REH3P21 antibody.
抗原
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