GRM7 抗体 (C-Term)
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Quick Overview for GRM7 抗体 (C-Term) (ABIN929284)
抗原
See all GRM7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- GRM7 antibody was raised in rabbit using the C terminal of GRM7 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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GRM7 Blocking Peptide, (ABIN939194), is also available for use as a blocking control in assays to test for specificity of this GRM7 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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别名
- GRM7
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背景
- L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. Synonyms: Polyclonal GRM7 antibody, Anti-GRM7 antibody, glutamate receptor, metabotropic 7 antibody, FLJ40498 antibody, GLUR7 antibody, GPRC1G antibody, MGLU7 antibody, MGLUR7 antibody.
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途径
- Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
抗原
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