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USP10 抗体 (C-Term)

The 兔 多克隆 anti-USP10 antibody (ABIN929190) specifically detects USP10 in WB. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN929190
发货至: 中国
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Quick Overview for USP10 抗体 (C-Term) (ABIN929190)

抗原

See all USP10 抗体
USP10 (Ubiquitin Specific Peptidase 10 (USP10))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This USP10 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    交叉反应

    大鼠

    纯化方法

    Purified

    免疫原

    Usp10 antibody was raised in rabbit using the C terminal of Usp10 as the immunogen
  • 应用备注

    Optimal conditions should be determined by the investigator.

    说明

    Usp10 Blocking Peptide, (ABIN5616928), is also available for use as a blocking control in assays to test for specificity of this Usp10 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    USP10 (Ubiquitin Specific Peptidase 10 (USP10))

    别名

    Usp10

    背景

    Usp10 is a hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. It acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Usp10 does not deubiquitinate MDM2 and deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling. Synonyms: Polyclonal Usp10 antibody, Anti-Usp10 antibody, ubiquitin specific peptidase 10 antibody, MGC124997 antibody.
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