USP10 抗体 (C-Term)
Quick Overview for USP10 抗体 (C-Term) (ABIN929190)
抗原
See all USP10 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
交叉反应
- 大鼠
-
纯化方法
- Purified
-
免疫原
- Usp10 antibody was raised in rabbit using the C terminal of Usp10 as the immunogen
-
-
-
-
应用备注
- Optimal conditions should be determined by the investigator.
-
说明
-
Usp10 Blocking Peptide, (ABIN5616928), is also available for use as a blocking control in assays to test for specificity of this Usp10 antibody
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
浓度
- Lot specific
-
缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
-
-
- USP10 (Ubiquitin Specific Peptidase 10 (USP10))
-
别名
- Usp10
-
背景
- Usp10 is a hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. It acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Usp10 does not deubiquitinate MDM2 and deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling. Synonyms: Polyclonal Usp10 antibody, Anti-Usp10 antibody, ubiquitin specific peptidase 10 antibody, MGC124997 antibody.
抗原
-