PDE8A 抗体 (C-Term)
Quick Overview for PDE8A 抗体 (C-Term) (ABIN928993)
抗原
See all PDE8A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- PDE8 A antibody was raised in rabbit using the C terminal of PDE8 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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PDE8A Blocking Peptide, (ABIN5615278), is also available for use as a blocking control in assays to test for specificity of this PDE8A antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- PDE8A (phosphodiesterase 8A (PDE8A))
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别名
- PDE8A
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背景
- Phosphodiesterases (PDEs) regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling. Synonyms: Polyclonal PDE8A antibody, Anti-PDE8A antibody, phosphodiesterase 8A antibody, FLJ16150 antibody, HsT19550 antibody.
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途径
- cAMP Metabolic Process
抗原
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