电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PSMD10 抗体 (N-Term)

PSMD10 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN928857
发货至: 中国
  • 抗原 See all PSMD10 抗体
    PSMD10 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10))
    抗原表位
    • 9
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 41
    • 10
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 36
    • 5
    克隆类型
    • 38
    • 3
    多克隆
    标记
    • 23
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMD10 antibody is un-conjugated
    应用范围
    • 28
    • 19
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    小鼠
    纯化方法
    Purified
    免疫原
    Psmd10 antibody was raised in rabbit using the N terminal of Psmd10 as the immunogen
    Top Product
    Discover our top product PSMD10 Primary Antibody
  • 应用备注
    Optimal conditions should be determined by the investigator.
    说明

    Psmd10 Blocking Peptide, catalog no. 33R-4354, is also available for use as a blocking control in assays to test for specificity of this Psmd10 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原
    PSMD10 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10))
    别名
    Psmd10 (PSMD10 产品)
    别名
    gankyrin antibody, zgc:109707 antibody, dJ889N15.2 antibody, p28 antibody, p28(GANK) antibody, AW554874 antibody, p28Gank antibody, proteasome 26S subunit, non-ATPase 10 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 antibody, psmd10 antibody, PSMD10 antibody, Psmd10 antibody
    背景
    Psmd10 acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly,Psmd10 is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module By similarity.Psmd10 acts as an oncoprotein by being involved in negative regulation of tumor suppressors RB1 and p53/TP53. Overexpression of this gene is leading to phosphorylation of RB1 and proteasomal degradation of RB1. Psmd10 regulates CDK4-mediated phosphorylation of RB1 by competing with CDKN2A for binding with CDK4. Synonyms: Polyclonal Psmd10 antibody, Anti-Psmd10 antibody, proteasome, prosome, macropain 26S subunit, non-ATPase, 10 antibody, AW554874 antibody.
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Ubiquitin Proteasome Pathway
You are here:
客服