GAD 抗体 (N-Term)
Quick Overview for GAD 抗体 (N-Term) (ABIN928718)
抗原
See all GAD (GAD1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 小鼠
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纯化方法
- Purified
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免疫原
- Gad1 antibody was raised in rabbit using the N terminal of Gad1 as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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Gad1 Blocking Peptide, (ABIN5613700), is also available for use as a blocking control in assays to test for specificity of this Gad1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
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别名
- Gad1
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背景
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Synonyms: Polyclonal Gad1 antibody, Anti-Gad1 antibody, glutamic acid decarboxylase 1 antibody.
抗原
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