SPA17 抗体 (N-Term)
Quick Overview for SPA17 抗体 (N-Term) (ABIN928702)
抗原
See all SPA17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Purified
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免疫原
- SPA17 antibody was raised in rabbit using the N terminal of SPA17 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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SPA17 Blocking Peptide, (ABIN5616350), is also available for use as a blocking control in assays to test for specificity of this SPA17 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- SPA17 (Sperm Autoantigenic Protein 17 (SPA17))
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别名
- SPA17
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背景
- This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22. Synonyms: Polyclonal SPA17 antibody, Anti-SPA17 antibody, sperm autoantigenic protein 17 antibody, SP17 antibody, SP17-1 antibody.
抗原
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