FTO 抗体 (N-Term)
Quick Overview for FTO 抗体 (N-Term) (ABIN928144)
抗原
See all FTO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 小鼠
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纯化方法
- Purified
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免疫原
- Fto antibody was raised in rabbit using the N terminal of Fto as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Fto Blocking Peptide, (ABIN5613650), is also available for use as a blocking control in assays to test for specificity of this Fto antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- FTO (Fat Mass and Obesity-Associated (FTO))
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别名
- Fto
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背景
- Fto is a dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Fto has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Fto has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Fto has no activity towards 1-methylguanine and no detectable activity towards double-stranded DNA. Fto requires molecular oxygen, alpha-ketoglutarate and iron. Fto contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Synonyms: Polyclonal Fto antibody, Anti-Fto antibody, fat mass and obesity associated antibody, AW743446 antibody, mKIAA1752 antibody.
抗原
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