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FTO 抗体 (N-Term)

This anti-FTO antibody is a 兔 多克隆 antibody detecting FTO in WB. Suitable for 人 和 小鼠.
产品编号 ABIN928144
发货至: 中国

Quick Overview for FTO 抗体 (N-Term) (ABIN928144)

抗原

See all FTO 抗体
FTO (Fat Mass and Obesity-Associated (FTO))

适用

  • 62
  • 27
  • 25
  • 5
  • 4
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 55
  • 8
  • 1
  • 1

克隆类型

  • 45
  • 20
多克隆

标记

  • 35
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FTO antibody is un-conjugated

应用范围

  • 52
  • 20
  • 15
  • 14
  • 14
  • 11
  • 11
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 12
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    交叉反应

    小鼠

    纯化方法

    Purified

    免疫原

    Fto antibody was raised in rabbit using the N terminal of Fto as the immunogen
  • 应用备注

    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    Fto Blocking Peptide, (ABIN5613650), is also available for use as a blocking control in assays to test for specificity of this Fto antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    FTO (Fat Mass and Obesity-Associated (FTO))

    别名

    Fto

    背景

    Fto is a dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Fto has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Fto has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Fto has no activity towards 1-methylguanine and no detectable activity towards double-stranded DNA. Fto requires molecular oxygen, alpha-ketoglutarate and iron. Fto contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Synonyms: Polyclonal Fto antibody, Anti-Fto antibody, fat mass and obesity associated antibody, AW743446 antibody, mKIAA1752 antibody.
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