RBM5 抗体 (N-Term)
Quick Overview for RBM5 抗体 (N-Term) (ABIN927731)
抗原
See all RBM5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
交叉反应
- 小鼠, 大鼠, 牛, 犬, Frog, 小鸡
-
纯化方法
- Purified
-
免疫原
- RBM5 antibody was raised in rabbit using the N terminal of RBM5 as the immunogen
-
-
-
-
应用备注
-
WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
-
RBM5 Blocking Peptide, (ABIN938939), is also available for use as a blocking control in assays to test for specificity of this RBM5 antibody
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
浓度
- Lot specific
-
缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
-
-
- RBM5 (RNA Binding Motif Protein 5 (RBM5))
-
别名
- RBM5
-
背景
- RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis. Synonyms: Polyclonal RBM5 antibody, Anti-RBM5 antibody, RNA binding motif protein 5 antibody, FLJ39876 antibody, G15 antibody, H37 antibody, LUCA15 antibody, RMB5 antibody.
-
途径
- Ribonucleoprotein Complex Subunit Organization
抗原
-