MAF 抗体 (N-Term)
Quick Overview for MAF 抗体 (N-Term) (ABIN927724)
抗原
See all MAF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 小鼠, 大鼠, 牛, 小鸡, 犬, 斑马鱼
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纯化方法
- Purified
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免疫原
- MAF antibody was raised in rabbit using the N terminal of MAF as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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MAF Blocking Peptide, (ABIN5614625), is also available for use as a blocking control in assays to test for specificity of this MAF antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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别名
- MAF
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背景
- MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context. Synonyms: Polyclonal MAF antibody, Anti-MAF antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog, avian antibody, MGC71685 antibody.
抗原
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