SNF8 抗体 (N-Term)
Quick Overview for SNF8 抗体 (N-Term) (ABIN927326)
抗原
See all SNF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 小鼠, 大鼠, Frog, 牛, 犬, 小鸡, 斑马鱼
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纯化方法
- Purified
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免疫原
- EAP30 antibody was raised in rabbit using the N terminal of EAP30 as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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EAP30 Blocking Peptide, catalog no. 33R-6102, is also available for use as a blocking control in assays to test for specificity of this EAP30 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
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别名
- EAP30
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背景
- ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia. In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25, and VPS36 form ESCRT-II, a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor. Synonyms: Polyclonal EAP30 antibody, Anti-EAP30 antibodyDot3 antibody, EAP30 antibody, VPS22 antibody.
抗原
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