CHRNA4 抗体 (N-Term)
Quick Overview for CHRNA4 抗体 (N-Term) (ABIN926962)
抗原
See all CHRNA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 小鼠, 大鼠, 牛, 小鸡
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纯化方法
- Purified
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免疫原
- CHRNA4 antibody was raised in rabbit using the N terminal of CHRNA4 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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CHRNA4 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CHRNA4 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
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别名
- CHRNA4
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背景
- CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Synonyms: Polyclonal CHRNA4 antibody, Anti-CHRNA4 antibody, cholinergic receptor, nicotinic, alpha 4 antibody, BFNC antibody, EBN antibody, EBN1 antibody, NACRA4 antibody.
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途径
- Synaptic Membrane
抗原
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