RPL7 抗体 (C-Term)
Quick Overview for RPL7 抗体 (C-Term) (ABIN926766)
抗原
See all RPL7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- RPL7 antibody was raised in rabbit using the C terminal of RPL7 as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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RPL7 Blocking Peptide, (ABIN936247), is also available for use as a blocking control in assays to test for specificity of this RPL7 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- RPL7 (Ribosomal Protein L7 (RPL7))
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别名
- RPL7
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背景
- Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Synonyms: Polyclonal RPL7 antibody, Anti-RPL7 antibody, ribosomal protein L7 antibody, MGC117326 antibody, humL7-1 antibody.
抗原
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