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VASP 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects VASP in WB. It exhibits reactivity toward 人.
产品编号 ABIN926692
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for VASP 抗体 (Middle Region) (ABIN926692)

抗原

See all VASP 抗体
VASP (Vasodilator-Stimulated phosphoprotein (VASP))

适用

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宿主

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克隆类型

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多克隆

标记

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This VASP antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    纯化方法

    Purified

    免疫原

    VASP antibody was raised in rabbit using the middle region of VASP as the immunogen
  • 应用备注

    Optimal conditions should be determined by the investigator.

    说明

    VASP Blocking Peptide, (ABIN935974), is also available for use as a blocking control in assays to test for specificity of this VASP antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    VASP (Vasodilator-Stimulated phosphoprotein (VASP))

    别名

    VASP

    背景

    Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. Synonyms: Polyclonal VASP antibody, Anti-VASP antibody, vasodilator-stimulated phosphoprotein antibody.

    途径

    TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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