ZAP70 抗体 (N-Term)
Quick Overview for ZAP70 抗体 (N-Term) (ABIN926687)
抗原
See all ZAP70 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Purified
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免疫原
- ZAP70 antibody was raised in rabbit using the N terminal of ZAP70 as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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ZAP70 Blocking Peptide, (ABIN5617066), is also available for use as a blocking control in assays to test for specificity of this ZAP70 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
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别名
- ZAP70
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背景
- This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. Synonyms: Polyclonal ZAP70 antibody, Anti-ZAP70 antibody, zeta-chain, TCR associated protein kinase 70kDa antibody, FLJ17670 antibody, FLJ17679 antibody, SRK antibody, STD antibody, TZK antibody, ZAP-70 antibody.
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途径
- TCR Signaling, Ubiquitin Proteasome Pathway
抗原
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