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ZAP70 抗体 (N-Term)

The 兔 多克隆 anti-ZAP70 antibody is suitable to detect ZAP70 in samples from 人. It has been validated for WB.
产品编号 ABIN926687
发货至: 中国
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Quick Overview for ZAP70 抗体 (N-Term) (ABIN926687)

抗原

See all ZAP70 抗体
ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

适用

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宿主

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克隆类型

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多克隆

标记

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This ZAP70 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    纯化方法

    Purified

    免疫原

    ZAP70 antibody was raised in rabbit using the N terminal of ZAP70 as the immunogen
  • 应用备注

    Optimal conditions should be determined by the investigator.

    说明

    ZAP70 Blocking Peptide, (ABIN5617066), is also available for use as a blocking control in assays to test for specificity of this ZAP70 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

    别名

    ZAP70

    背景

    This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. Synonyms: Polyclonal ZAP70 antibody, Anti-ZAP70 antibody, zeta-chain, TCR associated protein kinase 70kDa antibody, FLJ17670 antibody, FLJ17679 antibody, SRK antibody, STD antibody, TZK antibody, ZAP-70 antibody.

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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