Hexosaminidase A 抗体 (C-Term)
Quick Overview for Hexosaminidase A 抗体 (C-Term) (ABIN926663)
抗原
See all Hexosaminidase A (HEXA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- HEXA antibody was raised in rabbit using the C terminal of HEXA as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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HEXA Blocking Peptide, (ABIN5613994), is also available for use as a blocking control in assays to test for specificity of this HEXA antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Hexosaminidase A (HEXA)
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别名
- HEXA
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背景
- This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). Synonyms: Polyclonal HEXA antibody, Anti-HEXA antibody, hexosaminidase A, alpha polypeptide antibody, MGC99608 antibody, TSD antibody.
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途径
- Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
抗原
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