Vinculin 抗体 (C-Term)
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Quick Overview for Vinculin 抗体 (C-Term) (ABIN926662)
抗原
See all Vinculin (VCL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- VCL antibody was raised in rabbit using the C terminal of VCL as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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VCL Blocking Peptide, (ABIN5616950), is also available for use as a blocking control in assays to test for specificity of this VCL antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Vinculin (VCL)
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别名
- VCL
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背景
- Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. Synonyms: Polyclonal VCL antibody, Anti-VCL antibody, vinculin antibody, CMD1W antibody, CMH15 antibody, MVCL antibody.
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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