5HT1B Receptor 抗体 (N-Term)
Quick Overview for 5HT1B Receptor 抗体 (N-Term) (ABIN926037)
抗原
See all 5HT1B Receptor (HTR1B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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免疫原
- HTR1 B antibody was raised in rabbit using the N terminal of HTR1 as the immunogen
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anti-Serotonin Receptor 1B (HTR1B) (Internal Region) antibody
HTR1B 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (Internal Region) antibodyHTR1B 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (AA 1-49) antibodyHTR1B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (Cytoplasmic Domain) antibodyHTR1B 适用: 人, 大鼠, 小鼠, 犬, Bat, Cow, 豚鼠, Hamster, 兔, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (C-Term) antibodyVerified HTR1B 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (AA 33-49), (Extracellular) antibodyHTR1B 适用: 人 WB, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (AA 8-26) antibodyHTR1B 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (AA 261-310) antibodyHTR1B 适用: 人, 大鼠, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (AA 201-250) antibodyHTR1B 适用: 人, 大鼠, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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HTR1B Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this HTR1B antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))
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别名
- HTR1B
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背景
- The pathophysiology of depression remains enigmatic, although abnormalities that involve serotonin signaling have been implicated. The serotonin 1B receptor [5-hydroxytryptamine (5-HT1B) receptor] interacts with p11. p11 increases localization of 5-HT1B receptors at the cell surface. p11 is increased in rodent brains by antidepressants or electroconvulsive therapy, but decreased in an animal model of depression and in brain tissue from depressed patients. Overexpression of p11 increases 5-HT1B receptor function in cells and recapitulates certain behaviors seen after antidepressant treatment in mice. p11 knockout mice exhibit a depression-like phenotype and have reduced responsiveness to 5-HT1B receptor agonists and reduced behavioral reactions to an antidepressant. Synonyms: Polyclonal HTR1B antibody, Anti-HTR1B antibody, 5-hydroxytryptamine, serotonin receptor 1B antibody.
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途径
- JAK/STAT Signaling, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, S100 Proteins
抗原
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