PROCR 抗体
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北京 101111
Quick Overview for PROCR 抗体 (ABIN920711)
抗原
See all PROCR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The rat monoclonal antibody LMR-42 detects an outer-surface epitope of a 55 kDa plasma membrane protein over-expressed in several human non-Pgp multidrug-resistant (MDR) tumor cell lines. LMR-42 has potential value for the detection of EPCR, which may mediate anti-coagulant and anti-inflammatory functions along vascular endothelia. Whether and how anti-coagulant and anti-inflammatory functions of EPCR facilitate oncogenesis and/or drug-resistance is unclear.
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免疫原
- Expression cloning revealed that the LMR-42 antigen is identical to the human endothelial cell protein C receptor (EPCR). Protein C is the zymogen of the key anticoagulant enzyme, activated protein C (APC).
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亚型
- IgG2b
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应用备注
- Immunohistochemistry: Use at a 1:20 dilution on frozen sections, air-dried or acetone fixed cells. Flow cytometry: No cell permeabilization required.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 1 mL antibody (>200 tests) at 100 µg IgG/mL in serum-free culture supernatant with protein stabilizer and 0.1% sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- PROCR (Protein C Receptor, Endothelial (PROCR))
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别名
- Endothelial Cell Protein C Receptor
抗原
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