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ZWINT 抗体 (AA 85-170) (AbBy Fluor® 555)

This anti-ZWINT antibody is a 兔 多克隆 antibody detecting ZWINT in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN920501
发货至: 中国

Quick Overview for ZWINT 抗体 (AA 85-170) (AbBy Fluor® 555) (ABIN920501)

抗原

See all ZWINT 抗体
ZWINT (ZW10 Interactor (ZWINT))

适用

  • 45
  • 6
  • 3

宿主

  • 39
  • 7

克隆类型

  • 41
  • 5
多克隆

标记

  • 24
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ZWINT antibody is conjugated to AbBy Fluor® 555

应用范围

  • 34
  • 12
  • 12
  • 12
  • 7
  • 7
  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 12
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 85-170

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ZWINT

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ZWINT (ZW10 Interactor (ZWINT))

    别名

    ZWINT

    背景

    Synonyms: HZwint1, KNTC 2 AP, KNTC2AP, MGC 117174, MGC117174, ZW10 interacting protein 1, ZW10 interactor, ZWINT 1, ZWINT1, ZWINT-1, ZWINT_HUMAN.

    Background: ZWINT is a component of the MIS12 complex, which is required for kinetochore function and spindle checkpoint activity. ZWINT interacts with ZW10 and targets it to the kinetochore at prometaphase. ZWINT is detectable on the kinetochore till late anaphase. Inhibition of ZWINT expression results in chromosome missegregation, spindle checkpoint failure and, ultimately, cell death upon cytokinesis.

    基因ID

    11130
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