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SLAMF7 抗体 (AA 51-160) (AbBy Fluor® 488)

This anti-SLAMF7 antibody is a 兔 多克隆 antibody detecting SLAMF7 in WB 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN915406
发货至: 中国

Quick Overview for SLAMF7 抗体 (AA 51-160) (AbBy Fluor® 488) (ABIN915406)

抗原

See all SLAMF7 抗体
SLAMF7 (SLAM Family Member 7 (SLAMF7))

适用

  • 52
  • 23
  • 2
人, 小鼠

宿主

  • 38
  • 14
  • 3
  • 2

克隆类型

  • 41
  • 16
多克隆

标记

  • 32
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SLAMF7 antibody is conjugated to AbBy Fluor® 488

应用范围

  • 42
  • 22
  • 21
  • 15
  • 7
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 51-160

    交叉反应

    人, 小鼠

    预测反应

    Rat,Cow

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human SLAMF7

    亚型

    IgG
  • 应用备注

    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    SLAMF7 (SLAM Family Member 7 (SLAMF7))

    别名

    Slamf7/Cd319/Cs1

    背景

    Synonyms: 19A, 19A24 protein, CD 319, CD2 like receptor activating cytotoxic cells, CD2 subset 1, CD319, CD319 antigen, CRACC, CS1, Membrane protein FOAP 12, Novel Ly9, Novel LY9 lymphocyte antigen 9 like protein, Protein 19A, SLAM family member 7, SLAMF 7.

    Background: SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.

    UniProt

    Q9NQ25
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