Prostaglandin E Synthase 抗体 (PE-Cy5.5)
Quick Overview for Prostaglandin E Synthase 抗体 (PE-Cy5.5) (ABIN912491)
抗原
See all Prostaglandin E Synthase (PTGES) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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预测反应
- Mouse,Rat,Pig,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PTGEs
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亚型
- IgG
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应用备注
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Prostaglandin E Synthase (PTGES)
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别名
- PTGEs
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背景
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Synonyms: PGES, MPGES, PIG12, PP102, PP1294, MGST-IV, MGST1L1, TP53I12, mPGES-1, MGST1-L1, Prostaglandin E synthase, Microsomal glutathione S-transferase 1-like 1, Microsomal prostaglandin E synthase 1, p53-induced gene 12 protein, PTGES, MPGES1
Background: Prostaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2. It is a member of the MAPEG family. It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses.The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
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分子量
- 17kDa
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基因ID
- 9536
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UniProt
- O14684
抗原
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