PNPT1 抗体 (AA 551-650) (AbBy Fluor® 555)
Quick Overview for PNPT1 抗体 (AA 551-650) (AbBy Fluor® 555) (ABIN911616)
抗原
See all PNPT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 551-650
-
交叉反应
- 大鼠
-
预测反应
- Human,Mouse,Dog,Cow,Sheep,Horse
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human PNPT1
-
亚型
- IgG
-
-
anti-Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) (AA 1-783) antibody
PNPT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) (AA 489-538) antibodyPNPT1 适用: 人, 大鼠, 犬, 马, Cow, 豚鼠, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) (AA 1-783) antibodyPNPT1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) antibodyPNPT1 适用: 人 WB, IP, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) (N-Term) antibodyPNPT1 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) (Middle Region) antibodyPNPT1 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) antibodyPNPT1 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) (AA 551-650) antibodyPNPT1 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) (C-Term) antibodyPNPT1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) (C-Term) antibodyPNPT1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- PNPT1 (Polyribonucleotide Nucleotidyltransferase 1 (PNPT1))
-
别名
- PNPT1
-
背景
-
Synonyms: OLD35, DFNB70, PNPASE, old-35, COXPD13, Polyribonucleotide nucleotidyltransferase 1, mitochondrial, 3'-5' RNA exonuclease OLD35, PNPase old-35, Polynucleotide phosphorylase 1, PNPase 1, Polynucleotide phosphorylase-like protein, PNPT1
Background: RNA-binding protein implicated in numerous RNA metabolic processes. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'-to-5' direction. Mitochondrial intermembrane factor with RNA-processing exoribonulease activity. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Required for correct processing and polyadenylation of mitochondrial mRNAs. Plays a role as a cytoplasmic RNA import factor that mediates the translocation of small RNA components, like the 5S RNA, the RNA subunit of ribonuclease P and the mitochondrial RNA-processing (MRP) RNA, into the mitochondrial matrix. Plays a role in mitochondrial morphogenesis and respiration, regulates the expression of the electron transport chain (ETC) components at the mRNA and protein levels. In the cytoplasm, shows a 3'-to-5' exoribonuclease mediating mRNA degradation activity, degrades c-myc mRNA upon treatment with IFNB1/IFN-beta, resulting in a growth arrest in melanoma cells. Regulates the stability of specific mature miRNAs in melanoma cells, specifically and selectively degrades miR-221, preferentially. Plays also a role in RNA cell surveillance by cleaning up oxidized RNAs. Binds to the RNA subunit of ribonuclease P, MRP RNA and miR-221 microRNA.
-
基因ID
- 87178
-
UniProt
- Q8TCS8
抗原
-
