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PLSCR3 抗体 (AA 201-295) (HRP)

This anti-PLSCR3 antibody is a 兔 多克隆 antibody detecting PLSCR3 in ELISA, IHC (fro) 和 IHC (p). Suitable for 人.
产品编号 ABIN911527
发货至: 中国

Quick Overview for PLSCR3 抗体 (AA 201-295) (HRP) (ABIN911527)

抗原

See all PLSCR3 抗体
PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

适用

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宿主

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克隆类型

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多克隆

标记

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This PLSCR3 antibody is conjugated to HRP

应用范围

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ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 201-295

    预测反应

    Human,Mouse,Rat,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PLSCR3

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

    别名

    PLSCR3

    背景

    Synonyms: Ca2+-dependent phospholipid scramblase 3, Phospholipid scramblase 3, PL scramblase 3, PLS3, PLS3_HUMAN.

    Background: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

    基因ID

    57048

    途径

    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
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