PLCL1 抗体 (AA 1001-1096) (AbBy Fluor® 647)
Quick Overview for PLCL1 抗体 (AA 1001-1096) (AbBy Fluor® 647) (ABIN911380)
抗原
See all PLCL1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1001-1096
-
特异性
- This antibody may exhibit a slight secondary cross-reactivity with PLCL2 due to a 69 % non-sequential sequence similarity over the immunogen range.
-
交叉反应
- 小鼠
-
预测反应
- Human,Rat,Dog,Cow,Pig,Horse
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human PLCL1
-
亚型
- IgG
-
-
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- PLCL1 (phospholipase C-Like 1 (PLCL1))
-
别名
- PLCL1
-
背景
-
Synonyms: PLCL1, PLCE, Phospholipase C deleted in lung carcinoma, Phospholipase C epsilon, Phospholipase C like 1, Phospholipase C related but catalytically inactive protein, Phospholipase C related, but catalytically inactive protein, PLCE, PLCL, PRIP, Plcl1, C230017K02Rik, KIAA1092, PLC-L, PLC-L1, PLCE, PLCL, PRIP, PRIP-1, PLCL1_HUMAN.
Background: PLCL1 is involved an inositol phospholipid based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and sphatidylinositol. Component in the dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.
-
基因ID
- 5334
抗原
-