PAX8 抗体 (AbBy Fluor® 647)
Quick Overview for PAX8 抗体 (AbBy Fluor® 647) (ABIN910191)
抗原
See all PAX8 抗体适用
宿主
克隆类型
标记
应用范围
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                                            交叉反应
- Cow, 人, 小鼠, 大鼠
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                                            纯化方法
- Purified by Protein A.
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                                            免疫原
- KLH conjugated synthetic peptide derived from mouse PAX8
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                                            亚型
- IgG
 
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                                            应用备注
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                        FCM(1:100-500)
 IF(IHC-P)(1:100-500)
 Optimal working dilution should be determined by the investigator.
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
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                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            有效期
- 12 months
 
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    - PAX8 (Paired Box 8 (PAX8))
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                                            别名
- PAX8
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                                            背景
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                        Synonyms: Paired Box Gene 8, paired box homeotic gene 8, Paired box protein Pax 8, Paired Domain Gene 8, PAX 8,PAX-8, Background: This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells. 
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                                            分子量
- 50kDa
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                                            基因ID
- 18510
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                                            途径
- Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
 抗原
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