Cytokeratin 1 抗体 (AA 141-240) (AbBy Fluor® 555)
(1 reference)Quick Overview for Cytokeratin 1 抗体 (AA 141-240) (AbBy Fluor® 555) (ABIN909638)
抗原
See all Cytokeratin 1 (KRT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 141-240
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交叉反应
- Cow, 人, 小鼠, 大鼠
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预测反应
- Dog,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human pan cytokeratin
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亚型
- IgG
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anti-Keratin 1 (KRT1) (AA 141-240) antibody
KRT1 适用: 人, 大鼠, 小鼠, Cow WB, FACS, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) antibodyKRT1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Keratin 1 (KRT1) (AA 101-200) antibodyKRT1 适用: 人, 小鼠, 马 WB, FACS, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) (AA 487-644) antibodyKRT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) (AA 189-497) antibodyKRT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) (AA 267-438) antibodyKRT1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) (C-Term) antibodyKRT1 适用: 人, 大鼠 IHC, StM 宿主: 小鼠 Monoclonal LHK1 unconjugated
anti-Keratin 1 (KRT1) (AA 415-443) antibodyKRT1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18411 unconjugated
anti-Keratin 1 (KRT1) antibodyKRT1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Monoclonal 1C2 unconjugated
anti-Keratin 1 (KRT1) (AA 387-496) antibodyKRT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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: "Circulating Tumor Cells Expressing Markers of Tumor-Initiating Cells Predict Poor Survival and Cancer Recurrence in Patients with Pancreatic Ductal Adenocarcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 11, pp. 2681-2690, (2018) (PubMed).
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: "Circulating Tumor Cells Expressing Markers of Tumor-Initiating Cells Predict Poor Survival and Cancer Recurrence in Patients with Pancreatic Ductal Adenocarcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 11, pp. 2681-2690, (2018) (PubMed).
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- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
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别名
- Cytokeratin
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背景
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Synonyms: pan-cytokeratin, pan-CK, pan CK, P-CK, wide spectrum Cytokeratin, Cytokeratins, [cytokeratins 1, 2,4,5,6,7,8,71,72,75,78].
Background: Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for trichocytes. In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane. Numerous accessory proteins are involved in the genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms. Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation. Cytokeratins interact with desmosomes and hemidesmosomes, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection.
抗原
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