Lipin 1 抗体 (AA 501-600) (Cy5)
Quick Overview for Lipin 1 抗体 (AA 501-600) (Cy5) (ABIN904916)
抗原
See all Lipin 1 (LPIN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-600
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Rabbit,Chimpanzee,Goose
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Lipin 1
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亚型
- IgG
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anti-Lipin 1 (LPIN1) (AA 729-924) antibody
LPIN1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 201-300) antibodyLPIN1 适用: 大鼠, 小鼠 IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 741-890) antibodyLPIN1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 218-267) antibodyLPIN1 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 兔, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 792-890) antibodyLPIN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Lipin 1 (LPIN1) (AA 501-600) antibodyLPIN1 适用: 大鼠 IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 241-340) antibodyLPIN1 适用: 大鼠, 小鼠 IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 741-890) antibodyLPIN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (N-Term) antibodyLPIN1 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 兔, Cow, Pig, Saccharomyces cerevisiae, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 300-400), (Internal Region) antibodyLPIN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Lipin 1 (LPIN1)
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别名
- Lipin 1
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背景
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Synonyms: KIAA0188, LPIN1, PAP1, Phosphatidate phosphatase LPIN1, LPIN1_HUMAN.
Background: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
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基因ID
- 23175
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途径
- Monocarboxylic Acid Catabolic Process
抗原
-
