Ldha/Ldh 抗体 (AbBy Fluor® 350)
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北京 101111
Quick Overview for Ldha/Ldh 抗体 (AbBy Fluor® 350) (ABIN904663)
抗原
适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human LDH
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亚型
- IgG
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应用备注
- IF(IHC-P)(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Ldha/Ldh
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背景
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Synonyms: Lactate Dehydrogenase, Lactate Dehydrogenase Isoenzyme V, Lactate Dehydrogenase isozyme H4, L lactate dehydrogenase A chain, Lactate dehydrogenase A, Lactate dehydrogenase A chain, LDH A, LDH heart subunit, LDH M, LDHM, LDH muscle subunit, LDH1, LDHA, PIG 19, PIG19, Proliferation inducing gene 19 protein, TRG 5, TRG5, LDHA_HUMAN.
Background: The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.Lactate dehydrogenase is an enzyme present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. Isoforms of the enzyme include LDH 1 (4H) in the heart, LDH 2 (3H1M) in the reticuloendothelial system, LDH 3 (2H2M) in the lungs, LDH 4 (1H3M) in the kidneys and LDH 5 (4M) in the liver and striated muscle. The M and H subunits are encoded by two different genes.
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基因ID
- 3939
抗原
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