KLHL21 抗体 (AA 51-110) (AbBy Fluor® 350)
Quick Overview for KLHL21 抗体 (AA 51-110) (AbBy Fluor® 350) (ABIN903944)
抗原
See all KLHL21 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-110
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human KLHL21
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- KLHL21 (Kelch-Like 21 (KLHL21))
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别名
- KLHL21
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背景
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Synonyms: Kelch like protein 21, KIAA0469, KLHL21, MGC99635, KLH21_HUMAN.
Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
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基因ID
- 9903
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途径
- M Phase
抗原
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