KIFC1 抗体 (AbBy Fluor® 555)
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北京 101111
Quick Overview for KIFC1 抗体 (AbBy Fluor® 555) (ABIN903734)
抗原
See all KIFC1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- KIFC1 Polyclonal Antibody, AbBy Fluor-555 Conjugated
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交叉反应
- Cow, 人, 小鼠, Pig, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human KIFC1
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亚型
- IgG
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应用备注
- WB(WB=1:500-2000), IF(IF=1:100-500)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- KIFC1 (Kinesin Family Member C1 (KIFC1))
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别名
- KIFC1
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背景
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Synonyms: HSET KNSL2, K C1, KC 1, KC1, KC1_HUMAN, Kinesin family member C1, Kinesin like 2, Kinesin like protein 2, Kinesin like protein KC1, Kinesin related protein HSET, Kinesin-like protein 2, Kinesin-like protein KC1, Kinesin-related protein HSET, KNSL 2, KNSL2, Mitotic kinesin like protein 2, MKLP 2,
Background: The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIFC1 is a 673 amino acid protein that belongs to the kinesin-like family of proteins. KIFC1 localizes to the nucleus and contains a C-terminal kinesin-motor domain. Functioning as a minus-end directed microtubule-dependent motor, KIFC1 works together with NuMA and cytoplasmic Dynein to organize microtubule minus ends at spindle poles. HeLa cells deficient in KIFC1 exhibit multipolar mitotic spindles, suggesting that KIFC1 is essential for bipolar spindle formation.
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分子量
- 74kDa
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基因ID
- 3833
抗原
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