IER3 抗体 (AA 85-156) (FITC)
Quick Overview for IER3 抗体 (AA 85-156) (FITC) (ABIN901745)
抗原
See all IER3 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 85-156
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                                            交叉反应
- 大鼠
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                                            预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
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                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein
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                                            亚型
- IgG
 
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                                            应用备注
- 
                        IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            有效期
- 12 months
 
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    - IER3 (Immediate Early Response 3 (IER3))
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                                            别名
- IEX1
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                                            背景
- 
                        Synonyms: DIF2, IEX1, PRG1, DIF-2, GLY96, IEX-1, IEX-1L, Radiation-inducible immediate-early gene IEX-1, Differentiation-dependent gene 2 protein, Protein DIF-2, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, Protein PRG1, IER3 Background: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment. 
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                                            基因ID
- 8870
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                                            UniProt
- P46695
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                                            途径
- Regulation of Carbohydrate Metabolic Process
 抗原
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