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RNF144B 抗体 (AA 218-303) (Biotin)

This anti-RNF144B antibody is a 兔 多克隆 antibody detecting RNF144B in ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN901631
发货至: 中国

Quick Overview for RNF144B 抗体 (AA 218-303) (Biotin) (ABIN901631)

抗原

See all RNF144B 抗体
RNF144B (Ring Finger Protein 144B (RNF144B))

适用

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宿主

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克隆类型

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多克隆

标记

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This RNF144B antibody is conjugated to Biotin

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 218-303

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Cat,Rabbit,Guinea Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human IBRDC2/RING finger protein 144B

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    RNF144B (Ring Finger Protein 144B (RNF144B))

    别名

    RNF144B

    背景

    Synonyms: E3 ubiquitin protein ligase RNF144B, RING finger protein 144B, E3 ubiquitin-protein ligase RNF144B, IBR domain containing 2, IBR domain containing protein 2, IBR domain-containing protein 2, IBRDC 2, IBRDC2, p53 inducible RING finger protein, p53-inducible RING finger protein, p53RFP, PIR2, R144B_HUMAN, Ring finger 144B, RING finger protein 144B, RNF 144B, RNF144B.

    Background: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death, But, it is not an anti-apoptotic protein per se.Tissue specificity: Broadly expressed, with lowest levels in brain and thymus, and highest levels detectable in heart, ovary and testis.

    基因ID

    255488
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