GCKR 抗体 (AA 121-220) (Cy7)
Quick Overview for GCKR 抗体 (AA 121-220) (Cy7) (ABIN898538)
抗原
See all GCKR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-220
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GCKR
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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别名
- Glucokinase regulatory protein
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背景
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Synonyms: GKRP, FGQTL5, Glucokinase regulatory protein, Glucokinase regulator, GCKR
Background: Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
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基因ID
- 2646
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UniProt
- Q14397
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途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
抗原
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