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FOXL2 抗体 (AbBy Fluor® 488)

This anti-FOXL2 antibody is a 兔 多克隆 antibody detecting FOXL2 in WB 和 IF (p). Suitable for 人, 小鼠, 大鼠, Cow, Pig 和 犬.
产品编号 ABIN897561
发货至: 中国

Quick Overview for FOXL2 抗体 (AbBy Fluor® 488) (ABIN897561)

抗原

See all FOXL2 抗体
FOXL2 (Forkhead Box L2 (FOXL2))

适用

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人, 小鼠, 大鼠, Cow, Pig, 犬

宿主

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  • 1

克隆类型

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多克隆

标记

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This FOXL2 antibody is conjugated to AbBy Fluor® 488

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    Cow, 人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FOXL2

    亚型

    IgG
  • 应用备注

    IF(IHC-P)(1:100-500)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FOXL2 (Forkhead Box L2 (FOXL2))

    别名

    FOXL2

    背景

    Synonyms: blepharophimosis, Blepharophimosis epicanthus inversus and ptosis 1, Blepharophimosis epicanthus inversus and ptosis, BPES 1, BPES, BPES1, epicanthus inversus and ptosis 1, forkhead box L2, Forkhead box protein L2, forkhead transcription factor FOXL2, FOX L2, FOXL 2, FOXL2, FOXL2_HUMAN, PFRK, PINTO, POF 3, POF3.

    Background: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.

    分子量

    45-50kDa

    基因ID

    668

    途径

    Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity
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