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DUSP26 抗体 (AA 144-211) (Biotin)

This anti-DUSP26 antibody is a 兔 多克隆 antibody detecting DUSP26 in ELISA, WB, IHC (p) 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN894581
发货至: 中国

Quick Overview for DUSP26 抗体 (AA 144-211) (Biotin) (ABIN894581)

抗原

See all DUSP26 抗体
DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))

适用

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大鼠

宿主

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  • 1

克隆类型

  • 60
多克隆

标记

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This DUSP26 antibody is conjugated to Biotin

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
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    AA 144-211

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human DUSP26/MKP8

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))

    别名

    DUSP26

    背景

    Synonyms: DSP-4, Dual specicity phosphatase 26 putative, Dual specicity phosphatase 26, Dual specicity phosphatase SKRP3, Dual specicity protein phosphatase 26, DUS26_HUMAN, DUSP24, DUSP26, Hypothetical protein FLJ31142, LDP 4, LDP-4, Low molecular mass dual specicity phosphatase 4, Low-molecular-mass dual-specicity phosphatase 4, MAP kinase phosphatase 8, MGC1136, MGC2627, Mitogen activated protein kinase phosphatase 8, Mitogen-activated protein kinase phosphatase 8, MKP-8, MKP8, NATA1, NATA1 protein, Novel amplied gene in thyroid anaplastic cancer, SKRP3.

    Background: Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).Tissue specificity:Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer.

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