DOCK1 抗体 (AA 465-550) (Cy3)
Quick Overview for DOCK1 抗体 (AA 465-550) (Cy3) (ABIN894243)
抗原
See all DOCK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 465-550
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DOCK1
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
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别名
- DOCK1
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背景
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Synonyms: 180 kDa protein downstream of CRK, Ced5, Dedicator of Cytokinesis 1, Dedicator of cytokinesis protein 1, DOCK 1, DOCK-1, DOCK 180, DOCK1, DOCK1_HUMAN, DOCK180.
Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
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基因ID
- 1793
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途径
- Signaling of Hepatocyte Growth Factor Receptor
抗原
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