GM1123 抗体 (AA 21-120) (AbBy Fluor® 647)
Quick Overview for GM1123 抗体 (AA 21-120) (AbBy Fluor® 647) (ABIN892071)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-120
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Coxsackie Adenovirus Receptor
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亚型
- IgG
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anti-Predicted Gene 1123 (GM1123) (AA 21-120) antibody
GM1123 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GM1123 (Predicted Gene 1123 (GM1123))
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别名
- Coxsackie Adenovirus Receptor
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背景
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Synonyms: CAR, HCAR, CAR4/6, Coxsackievirus and adenovirus receptor, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, HCVADR, CXADR
Background: Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
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基因ID
- 1525
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UniProt
- P78310
抗原
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