Corin 抗体 (PE)
Quick Overview for Corin 抗体 (PE) (ABIN891982)
抗原
See all Corin (CORIN) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Excitation / Emission Wavelengths: 565nm/578nm
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交叉反应
- 大鼠, 犬, 猪
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纯化方法
- purified by Protein A
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免疫原
- KLH conjugated synthetic peptide derived from human Corin
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亚型
- IgG
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anti-Corin, Serine Peptidase (CORIN) (AA 134-573) antibody
CORIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Corin, Serine Peptidase (CORIN) (AA 165-245) antibodyCORIN 适用: 人, 大鼠, 绵羊 ELISA, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Corin, Serine Peptidase (CORIN) (AA 807-1038) antibodyCORIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Corin, Serine Peptidase (CORIN) (AA 70-136) antibodyCORIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Corin, Serine Peptidase (CORIN) (AA 533-634) antibodyCORIN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Corin, Serine Peptidase (CORIN) (AA 616-715) antibodyCORIN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-Corin, Serine Peptidase (CORIN) (AA 334-477) antibodyCORIN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Corin, Serine Peptidase (CORIN) (AA 1-110) antibodyCORIN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Corin, Serine Peptidase (CORIN) (AA 616-715) antibodyCORIN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Corin, Serine Peptidase (CORIN) (AA 881-930) antibodyCORIN 适用: 人, 大鼠, 小鼠, Cow, 马, 豚鼠, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
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说明
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Excitation / Emission wavelength: 496nm / 578nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 µg/µL
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缓冲液
- Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 4 °C for 12 months
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有效期
- 12 months
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- Corin (CORIN) (Corin, Serine Peptidase (CORIN))
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别名
- Corin
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背景
- Corin was first described as a trypsin-like serine proteinase in the heart which processed pro-atrial natriuretic peptide into the active form ANP. Corin cleaves pro-ANP at Arg98/Ser-99, and blocking Corin message inhibits pro-ANP processing. Null mutant mice lacking Corin develop hypertension, and a series of missense mutations have been identified in humans with high blood pressure and hypertension. Corin is a member of the type-II transmembrane serine proteinases, such as Hepsin, Epitheliasin, Matriptase and enteropeptidase. The Corin domain structure includes a cytoplasmic domain, a transmembrane domain, a spacer region, a frizzled-like domain, 5 LDL Receptor-like domains, another frizzled-like domain, 3 more LDLR-like repeats, a SRCR (Scavenger Receptor-Cysteine Rich) domain (also called macrophage scavenger-like domain), and finally the trypsin-like serine proteinase domain. The complex domain structure puts Corin into the ﾓmosaicﾔ TMPRSS family, so named because of the wide variety of domains.
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分子量
- 117kDa
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基因ID
- 10699
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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