SETDB2 抗体 (AA 21-120) (HRP)
Quick Overview for SETDB2 抗体 (AA 21-120) (HRP) (ABIN891348)
抗原
See all SETDB2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 21-120
-
交叉反应
- 大鼠
-
预测反应
- Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human CLLD8/SETDB2
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
-
别名
- CLLD8
-
背景
-
Synonyms: Histone-lysine N-methyltransferase SETDB2, C13orf4, Chromosome 13 open reading frame 4, Chronic lymphocytic leukemia deletion region 8, Chronic lymphocytic leukemia deletion region gene 8, Chronic lymphocytic leukemia deletion region gene 8 protein, Clld8, CLLL8, Gm293, H3-K9-HMTase, Histone H3-K9 methyltransferase, KMT1F, Lysine N-methyltransferase 1F, Probable histone-lysine N-methyltransferase H3 lysine-9 specic, SEB2, SET domain burcated 2, SET domain protein, burcated, 2, SETB2_HUMAN, Setdb2.
Background: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
-
基因ID
- 83852
抗原
-