CLASP2 抗体 (AA 1201-1294) (Cy5)
Quick Overview for CLASP2 抗体 (AA 1201-1294) (Cy5) (ABIN891146)
抗原
See all CLASP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1201-1294
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预测反应
- Human,Mouse,Rat,Dog,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CLASP2
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))
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别名
- CLASP2
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背景
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Synonyms: CLASP 2, CLIP associating protein 2, Cytoplasmic linker associated protein 2, hOrbit2, KIAA0627, Multiple asters Mast like homolog 2, Protein Orbit homolog 2, CLAP2_HUMAN.
Background: CLASP2 is a microtubule plus end tracking protein that promotes the stabilization of dynamic microtubules and is required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. CLASP2 may act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3 kinase signaling. CLASP2 also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
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基因ID
- 23122
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途径
- Microtubule Dynamics, Maintenance of Protein Location
抗原
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