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KRT12 抗体 (AA 151-250) (AbBy Fluor® 555)

This anti-KRT12 antibody (ABIN890815) is a Rabbit Polyclonal antibody detecting KRT12 in WB, IF (cc), IF (p). Suitable for Human, Mouse.
产品编号 ABIN890815
发货至: 中国

Quick Overview for KRT12 抗体 (AA 151-250) (AbBy Fluor® 555) (ABIN890815)

抗原

See all KRT12 抗体
KRT12 (Keratin 12 (KRT12))

适用

  • 39
  • 18
  • 11
  • 1
人, 小鼠

宿主

  • 43
  • 3
  • 1

克隆类型

  • 45
  • 2
多克隆

标记

  • 22
  • 7
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KRT12 antibody is conjugated to AbBy Fluor® 555

应用范围

  • 40
  • 21
  • 12
  • 12
  • 12
  • 9
  • 7
  • 6
  • 5
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 8
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 151-250

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CK12/Cytokeratin 12

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    KRT12 (Keratin 12 (KRT12))

    别名

    CK12

    背景

    Synonyms: 65 kDa cytokeratin, CK 12, CK 3, CK12, CK3, Cytokeratin 12, Cytokeratin 3, K12, K3, keratin 12 Meesmann corneal dystrophy, Keratin 12, Keratin 3, Keratin, type I cytoskeletal 12, K1C12_HUMAN, Keratin, type II cytoskeletal 3, KRT12, KRT3.

    Background: Cytokeratin 12 is a member of the intermediate filament family of proteins and is a heterotetramer of two type I and two type II keratins. Keratin 3 is specifically expressed in the corneal epithelium with family member KRT12. Cytokeratin 12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Defects in KRT3 and KRT12 are a cause of Meesmann corneal dystrophy (MCD), an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Symptoms occur in adulthood and include rupture of the corneal microcysts that may lead to photophobia, contact lens intolerance and intermittent diminution of visual acuity. Defects in KRT12 are a cause of juvenile epithelial corneal dystrophy of Meesmann (MCD)

    分子量

    54kDa

    基因ID

    3859
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