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CDC14B 抗体 (AA 65-160) (HRP)

This 兔 多克隆 antibody specifically detects CDC14B in ELISA, IHC (fro) 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN889453
发货至: 中国
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Quick Overview for CDC14B 抗体 (AA 65-160) (HRP) (ABIN889453)

抗原

See all CDC14B 抗体
CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

适用

人, 小鼠, 大鼠

宿主

  • 27
  • 4

克隆类型

  • 31
多克隆

标记

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CDC14B antibody is conjugated to HRP

应用范围

  • 13
  • 13
  • 11
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-160

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CDC14B

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

    别名

    CDC14B

    背景

    Synonyms: CDC14B3, Cdc14B1, Cdc14B2, hCDC14B, Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, CDC14B

    Background: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.

    基因ID

    8555

    UniProt

    O60729
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