SIRPA 抗体 (C-Term) (PE-Cy5.5)
Quick Overview for SIRPA 抗体 (C-Term) (PE-Cy5.5) (ABIN888881)
抗原
See all SIRPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Excitation / Emission Wavelengths: 480,565,675nm/694nm
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交叉反应
- 大鼠, 小鼠, 兔, 猪, 牛, 马
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纯化方法
- Antibodies are purified by protein A and peptide affinity chromatography.
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免疫原
- KLH conjugated synthetic peptide derived from human CD172a
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亚型
- IgG
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anti-Signal-Regulatory Protein alpha (SIRPA) (AA 28-507) antibody
SIRPA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C7 unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 235-373) antibodySIRPA 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2H7E2 unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 395-504) antibodySIRPA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 105-324) antibodySIRPA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 56-296) antibodySIRPA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (C-Term) antibodySIRPA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) antibodySIRPA 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 151-250) antibodySIRPA 适用: 人, 小鼠 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 31-373) antibodySIRPA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) antibodySIRPA 适用: Pig WB, FACS, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal BL1H7 unconjugated
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应用备注
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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储存条件
- -20 °C
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- SIRPA (Signal-Regulatory Protein alpha (SIRPA))
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别名
- SIRP Alpha
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背景
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Protein tyrosine phosphatases (PTPases) SHP1 and SHP2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPa (1),SHPS1 , MyD1, BIT and p84. SIRPa is a new gene family containing at least fifteen members. SIRPa is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP2. SIRPa has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.
Synonym: Signal regulatory protein alpha type 1, BIT, Brain Ig like molecule with tyrosine based activation motifs, Brain immunoglobulin like molecule with tyrosine based activation motifs, CD172 antigen like family member A, CD172a, CD172a antigen, Inhibitory receptor SHPS1, Macrophage fusion receptor, MFR, MYD 1, Myd 1, MYD1, p84,Protein tyrosine phosphatase non receptor type substrate 1, PTPNS1, SHP Substrate 1, SHPS1, Signal regulatory protein alpha 2, Signal regulatory protein alpha 3, Signal regulatory protein alpha, Signal Regulatory Protein Alpha Type 1, Signal regulatory protein alpha type 2, SIRP, SIRPA, SIRPalpha, SIRPalpha1, SIRPalpha2, SIRPalpha3, Tyrosine phosphatase SHP substrate 1, Tyrosine protein phosphatase non receptor type substrate 1, Tyrosine protein phosphatase non receptor type substrate. -
分子量
- 56kDa
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基因ID
- 140885
抗原
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