BMP1 抗体 (AbBy Fluor® 647)
Quick Overview for BMP1 抗体 (AbBy Fluor® 647) (ABIN885196)
抗原
See all BMP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human BMP1
-
亚型
- IgG
-
-
anti-Bone Morphogenetic Protein 1 (BMP1) (AA 284-296) antibody
Verified BMP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 1 (BMP1) antibodyBMP1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB56808 unconjugated
anti-Bone Morphogenetic Protein 1 (BMP1) (AA 131-180) antibodyBMP1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 1 (BMP1) (AA 610-843) antibodyBMP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 1 (BMP1) (AA 747-845) antibodyBMP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 1 (BMP1) (AA 225-617) antibodyBMP1 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-Bone Morphogenetic Protein 1 (BMP1) (AA 957-986) antibodyBMP1 适用: 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 1 (BMP1) antibodyBMP1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 1 (BMP1) (AA 361-410) antibodyBMP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 1 (BMP1) (AA 317-424) antibodyBMP1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- BMP1 (Bone Morphogenetic Protein 1 (BMP1))
-
别名
- Bmp1
-
背景
-
Synonyms: BMP 1, BMP-1, Bone morphogenetic protein 1, Mammalian tolloid protein, mTld, PCOLC, PCP, ProCollagen C endopeptidase, Procollagen C proteinase, TLD, BMP1_HUMAN.
Background: Bone morphogenetic protein 1 (BMP1) was first identified in osteogenic extracts of bone. It is an extracellular zinc endopeptidase, implicated in morphogenetic processes in a broad range of species. BMP1 is a member of the astacin family of metalloproteinases. The astacin family includes BMP1, astacin, meprin A and B, tolloid-like proteins, and choriolysin. BMP1 is involved in extracellular matrix (ECM) formation, suggesting that a functional link may exist between astacin metalloproteinases, growth factors, and cell differentiation and pattern formation during development. The name PCP reflects this enzyme’s involvement in the collagen deposition of growing bone. The enzymes known as the procollagen C and N proteinases (PCP and PNP) are involved in the processing of fibrillar procollagen precursors to mature collagens, which is an essential requirement for fibril formation. PCP cleaves the C-terminus from procollagen, to allow the formation of mature, triplehelical collagen. The N-terminus is cleaved by the procollagen N-proteinase (PNP or ADAM-TS2). Defects in PNP have been linked to the skin disorder dermatosparaxis, and defects in BMP1 are thought to lead to aberrant collagen processing, and connective tissue disorders. Many forms of BMP1 have been reported, with varying truncation at the C-terminus. The long form of BMP1 is most similar to the tolloid-like proteins, which have extra EGF-like and CUB domains.
-
基因ID
- 649
-
途径
- Lipid Metabolism
抗原
-
